Off-Label Drug Use in Pediatrics The unapproved use of approved drugs, also called off-label use, with children is quite common. This is because pediatric dosage guidelines are typically unavailable since very few drugs have been specifically researched and tested with children. When treating children, prescribers often adjust dosages approved for adults to accommodate a child’s weight. However, children are not just “smaller” adults. Adults and children process and respond to drugs differently in their absorption, distribution, metabolism, and excretion. Children even respond differently during stages from infancy to adolescence. This poses potential safety concerns when prescribing drugs to pediatric patients. As an advanced practice nurse, you have to be aware of safety implications of the off-label use of drugs with this patient group. To prepare: · Review the Panther et al (2017) and Corney, Lebel, Bailey, and Bussieres (2015) articles in the Learning Resources. Reflect on situations in which children should be prescribed drugs for off-label use. · Think about strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Consider specific off-label drugs that you think require extra care and attention when used in pediatrics. With these thoughts in mind: Write Include sub headings plz. And purpose of writing. · an explanation of circumstances under which children should be prescribed drugs for off-label use. · Then, describe strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. · Include descriptions and names of off-label drugs that require extra care and attention when used in pediatrics. Points to follow when writing a paper:

Philosophy Class
September 18, 2020
Discussion Questions
September 18, 2020
0

Off-Label Drug Use in Pediatrics The unapproved use of approved drugs, also called off-label use, with children is quite common. This is because pediatric dosage guidelines are typically unavailable since very few drugs have been specifically researched and tested with children. When treating children, prescribers often adjust dosages approved for adults to accommodate a child’s weight. However, children are not just “smaller” adults. Adults and children process and respond to drugs differently in their absorption, distribution, metabolism, and excretion. Children even respond differently during stages from infancy to adolescence. This poses potential safety concerns when prescribing drugs to pediatric patients. As an advanced practice nurse, you have to be aware of safety implications of the off-label use of drugs with this patient group. To prepare: · Review the Panther et al (2017) and Corney, Lebel, Bailey, and Bussieres (2015) articles in the Learning Resources. Reflect on situations in which children should be prescribed drugs for off-label use. · Think about strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Consider specific off-label drugs that you think require extra care and attention when used in pediatrics. With these thoughts in mind: Write Include sub headings plz. And purpose of writing. · an explanation of circumstances under which children should be prescribed drugs for off-label use. · Then, describe strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. · Include descriptions and names of off-label drugs that require extra care and attention when used in pediatrics. Points to follow when writing a paper:

Discussion: Disorders of the Reproductive Systems

While the male and female reproductive systems are unique to each sex, they share a common function—reproduction. Disorders of this system range from delayed development to structural and functional abnormalities. Since many reproductive disorders not only result in physiological consequences but also psychological consequences such as embarrassment, guilt, or profound disappointment, patients are often hesitant to seek treatment. Advanced practice nurses need to educate patients on disorders and help relieve associated stigmas. During patient evaluations, patients must feel comfortable answering questions so that you, as a key health care provider, will be able to diagnose and recommend treatment options. As you begin this Discussion, consider reproductive disorders that you would commonly see in the clinical setting.

To Prepare

  • Review      Chapter 22 and Chapter 23 in the McPhee and Hammer text, as well as      Chapter 33 and 34 in the Huether and McCance text.
  • Select two disorders      of the male and/or female reproductive systems that interest you. Consider      the similarities and differences between the disorders.
  • Select one of the      following factors: genetics, ethnicity, age, or behavior. Think about how      the factor you selected might impact the diagnosis of and treatment for      the reproductive disorders.

Write Include sub headings plz. And purpose of writing.

· A description of the two reproductive disorders you selected, including their similarities and differences. I am looking for an explanation at the cellular or molecular level (whenever possible

· Then explain how the factor you selected might impact the diagnosis of treatment for the reproductive disorders.

  • attachment

    Discussionwk11pathosyl.docx
 
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